TTX Converts Polymorphic VT to Monomorphic VT in Transgenic Rabbit Model of LQT1

Recurrent infection in a late presentation of catecholaminergic polymorphic VT.

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by episodic syncope resulting from fast VT (bidirectional or polymorphic) occurring during exercise/acute emotion in individuals without structural cardiac abnormalities. Mean age of onset is between seven and nine years, although onset as late as the fourth decade of life has been reported. We present the oldest repo...

Reuse: Revisiting Sisyphus-VT

Reuse has long been a major goal of the Knowledge Engineering community. The focus of this paper is the reuse of domain knowledge acquired for an initial problem solver, with a further problem solver. For our analysis we chose a knowledge base system written in CLIPS based on the propose-andrevise (PnR) problem solver, and which had a lift/elevator knowledge base (KB). Given the nature of the p...

Editorial: the Sisyphus-VT initiative

This special issue contains results of the second ‘‘Sisyphus’’ study carried out in the knowledge acquisition community in the period 1992 – 1995 . The Sisyphus initiative arose at the 1990 European Knowledge Acquisition Workshop in Driebergen (The Netherlands) . To explain the rationale behind this initiative it is necessary to give a brief synopsis of the recent history of the knowledge-engin...

Parameterized VT area function inversion

The purpose of our study is to contribute tools for inversion of articulatory to acoustics relations, in specific to perform an estimate of vocal tract area-function parameters from formant frequencies. The inversion is performed in two steps. A first approximation is attained from either a codebook or a neural net and a final optimization is performed by an iterative interpolation for finding ...

Current Issues in ICD SVT-VT Discrimination: Pacing for SVT-VT Discrimination